Kirli Sepeti will tell the story of women working as maids in a luxurious villa. The series will start with the suicide of a cleaner named Meryem, who jumps out of a window in the villa where she works. Meryem's suicide, full of secrets, will affect Songül, who works as a cleaner in the same complex, and her daughter İlkgül, who is studying at university, the most. Director Merve Girgin has prepared the series with the slogan "We cleaned their houses, not their hearts.
Cennet, who has been abused by her husband for years, gets sick and is hospitalized. While her treatment continues, she sees Lawyer Zeynep's number on the window of the hospital and calls for help. Cennet gives her a letter to open after she dies. This letter brings Cennet's eldest son Halil and Zeynep together, but it also causes a conflict between the brothers. Although Halil and Zeynep come together for Cennet, a romance begins between them.