A brilliant crossword puzzle editor finds her life turned upside-down when she is pulled into a police investigation after several of the clues in her recent puzzles are linked to unsolved crimes. The lure of an unsolved puzzle leads to an unlikely partnership working with a tough, but charming police detective as the two set out to solve the murder before the killer strikes again.

The show is based on the novel by Kate Collins. Abby Knight, a former lawyer turned flower shop owner, is starting over after the death of her husband with the support of her father and her daughter, who recently left for college. Life is good in the peaceful town of New Chapel, but when an SUV rams her prized vintage car, she's determined to track down the driver. She begrudgingly accepts the help of a new neighbor, the handsome and charming ex-Marine Marco Salvare. But their budding relationship is threatened when an acquaintance is murdered and Abby's good friend is the prime suspect - and it all links back to the hit and run. Caught up in a tangle of menacing phone calls, police corruption and murderous road rage, Abby must work against the clock to find the killer or the next flower arrangement might be for her own funeral.

The show goes behind-the-scenes of a hit competition dating show to follow the experiences of a young staffer whose sole job is to manipulate her relationships with (and among) the contestants to get the vital dramatic and outrageous footage the program's producers demand. What ensues is a humorous, yet vexing, look at what happens in the world of unscripted television, where being a contestant can be vicious and producing it is a whole other reality.

A young caterer's life suddenly changes course when she inherits a country home and learns she must share it with a career-obsessed Wall Street trader. At first, these opposites do not attract, but feelings begin to change when they find themselves having to work side-by-side to restore their newly acquired home.

Andie MacDowell plays Judge Olivia Lockhart, whose Cedar Cove Municipal Court is the professional milieu and social microcosm of issues the judge will face in her own day-to-day life with family and friends. Jack Griffith, the editor of the Cedar Cove Chronicle, is a new friend and potential love interest for Judge Lockhart.

Their worlds couldn't be more different but their commitment and passion brings them together. Strong Medicine is a sometimes intense, sometimes hilarious medical drama that takes us inside the world of street level medicine.