Dating coach Bo-ra, whose relationship is failing, and prickly publisher Su-hyeok team up to save Bo-ra's love life for the sake of her upcoming book about dating. The collaboration results in the mind game of romance.
My Holo Love follows the unique story of three not-so-perfect but extraordinary characters. So Yun has distanced herself from the rest of the world due to her face blindness disorder. Holo and Nan Do look exactly the same but are polar opposites. Holo is a perfect AI assistant who realizes his limits as an artificial intelligence. Nan Do is Holo's developer who begins to have feelings for So Yun, while watching her and Holo interact.
Lee Young-Joon's family runs a large company and he works as the vice-president of the company. He is smart, rich and handsome, but he is arrogant. His secretary is Kim Mi-So. She has worked for him for years and she is perfect for him, but Kim Mi-So decides to quit her job.