Set within the competitive power struggles of TV home shopping hosts, three hosts compete each other with intense desires to achieve success and gain fame in the industry field. Among them is Hyun, who has a mundane and just ordinary career. Because she does not get much shine as Ok-sun, she falls in anxiety.
Nam Shin is the son of a family who runs a large company. After an unexpected accident he falls into a coma. His mother, Oh Ro Ra, is an authority on brain science and artificial intelligence. She creates an android named Nam Shin III which looks just like her son. The android pretends to be Nam Shin and has a bodyguard, Kang So Bong.
Mrs. Cop follows the story of Choi Yeong Jin, a tough and dedicated detective who takes a break from work, leaving her position to the FBI-trained Ko Yoon Jung.
Ko Yoon Jung faces the challenge of filling Choi Yeong Jin's shoes while dealing with her own past traumas. The series explores the complexities of crime-solving and the personal struggles of its characters.