in Hyuk is a genius neurosurgeon with a cold and severe attitude in his interactions with other people due to his personal pursuit of perfection. Through a mysterious power, Jin Hyuk finds himself transported back in time 150 years. He begins treating people there, but the lack of necessary implements and rudimentary medical knowledge of the period forces him to seek new ways to aid the sick. Through this challenging process, Jin Hyuk eventually becomes a genuine doctor.
Set during the reign of King Sukjong in the Joseon dynasty, the story focuses on Dong Yi, a water maid who gains the trust of Queen Inhyeon and later the favour of the king when he is moved by her prayers for the health of the Queen during the court disputes caused by Jang Hee Bin. Dong Yi becomes a concubine with the rank of sook-bin and bears a son who will later become the 21st king of Joseon, Yeongjo.
The show pairs up Korean celebrities to show what life would be like if they were married. Each week, couples have assigned missions to complete, with candid interviews of the participants to reveal their thoughts and feelings.