Kang Pil-Joo grew up at an orphanage, but he now works as a managing director of a legal team at a corporation. He is acknowledged for his intelligence and his exemplary job performance. Some of those that work around him are jealous of him. Na Mo-Hyun is an environmental activist and a science teacher at a middle school. She is a good listener and laughs a lot. She dreams of a love driven by fate.
How dangerous is a genius neurosurgeon who is incapable of having any feelings for his patients? Lee Young Oh is the best at what he does but because of an accident in his frontal lobe, he lacks sympathy for his patients and has erratic personalities. When a series of bizarre patient deaths occur at the hospital, police investigators converge around Young Oh. Can a rookie cop help Young Oh open up his heart and learn to love again?
Several students in an underachieving class in their second year of high school face conflict in their academic and personal lives. They also have to deal with simply growing up and becoming who they want to be - something their teachers attempt to guide them through even as they come across similar problems of their own.
The show pairs up Korean celebrities to show what life would be like if they were married. Each week, couples have assigned missions to complete, with candid interviews of the participants to reveal their thoughts and feelings.