Robbie Rist

Dottie "Doc" McStuffins is a nurturing 6-year-old girl who cares for stuffed animals and toys in her playhouse clinic. When she puts on her stethoscope, something magical happens - toys, dolls and stuffed animals come to life and she can communicate with them. Like any good doctor, Doc has assistants helping her at her clinic. Her stuffed animal friends who assist Doc include exceedingly proud dragon Stuffy, cuddly best friend Lambie and caring hippo nurse Hallie. Whether it's loose stitching, low batteries or a blow-up toy that has sprung a leak, Doc and her friends are there to fix up the stuffed animals and toys.

Only the first three episodes of the series, comprising the pilot movie, feature a title sequence beginning with "Galactica 1980". The remaining episodes begin by calling the show "Battlestar Galactica", as if this were the second season of the original show.

The show centers around a forty-year-old middle school science teacher named John Martin (played by Edelman). While vacationing in Florida, he drinks from a spring which turns out to be the legendary Fountain of Youth sought by Juan Ponce de Leon. The water has the effect of changing him into a twelve-year-old boy (played by Rist), and back again. Martin has no control over when the changes will occur, because he only took a sip of the water, and not a full drink, which explains why the changes are recurring and not permanent. Only his wife, Marjorie (Joyce Bulifant) and son, Ricky (Mike Darnell) know his secret, though Martin's students (who befriend him as "Little John") and his boss, principal Bertha Bottomly, become suspicious that something unusual is going on. The Martin family explain the younger John as their nephew, staying with them. Throughout the series, "Big John" unsuccessfully tries to find a cure for his predicament, but his experiences as "Little John" often give him insight into what his students are facing.