Jin Hee, a dietitian, and Chang Min, a medical student, fall in love and marry despite Chang Min's family's disapproval. Chang Min gave up his medical internship and started working as a pharmaceutical salesman. Ultimately, their marriage is not a happy one and Chang Min's family's constant disapproval of Jin Hee leads to him treating her poorly. They divorce and try to go their separate ways until they become interns for the same hospital.

This show is classified as an "urban action variety"; a never-before-seen new genre of variety shows focused in an urban environment. The MCs and guests complete missions in a landmark to win the race. The show has since shifted to a more familiar reality-variety show concept focused on games.

Love, tradition, and politics collide when a spirited young art student is betrothed to the crown prince of South Korea.